André Pichette

Chercheur régulier
Chimie des produits naturels

Université du Québec à Chicoutimi
Pavillon principal
Département des sciences fondamentales
Bureau P4-2080
555, boulevard de l’Université
Chicoutimi (Québec) G7H 2B1

Tél.: 418 545-5011 poste 5081 ou 1 800 463-9880 poste 5081 (sans frais)

Page départementale à l'UQAC  | Page au LASEVE 

FORMATION

• Études post-doctorales à Santé Canada (Ottawa)
• Ph. D. en sciences du bois (Université Laval)
• M. Sc. en chimie (Université de Sherbrooke)
• Baccalauréat en chimie (UQAC)

THÈMES DE RECHERCHE

• Identification de produits naturels bio-actifs
• Développement d’approches de production de molécules à haute valeur ajoutée
• Préparation d’analogues de produits naturels bio-actifs
• Analyse de produits naturels volatils

PUBLICATIONS

Livres

1. Simard, F., Pichette, A., Legault, J. (2012) New Bioactive Natural Products from Canadian Boreal Forest. 241-258 p

Chapitres de livre

Aucun

Livres, numéros spéciaux et actes de colloques publiés à titre d'éditeur

Aucun

Articles révisés par un comité de lecture

1. Belanger, A., Pichette, A., Gauthier, M., Legault, J. (2024) Diphoterine, an amphoteric rinsing solution, reduces hydrofluoric acid injuries in an ex vivo pigskin model. Burns, 50(2):488 – 494
2. Gauthier, C., Lavoie, S., Kubicki, S., Piochon, M., Cloutier, M., Dagenais-Roy, M., Groleau, M.-C., Pichette, A., Thies, S., Deziel, E. (2024) Structural characterization of a nonionic rhamnolipid from Burkholderia lata. Carbohydrate Research, 535
3. Karker, M., Oueslati, S., Falleh, H., Msaada, K., Legault, J., Abdelly, C., Pichette, A., Ksouri, R. (2024) Phytochemical investigation, antioxidant, anti-inflammatory and cytotoxic activities of Tunisian medicinal Tamarix africana Poir. International Journal of Environmental Health Research, 34(5):2366 – 2377
4. Sylla, B., Jost, G., Lavoie, S., Legault, J., Gauthier, C., Pichette, A. (2024) Synthesis and cytotoxicity evaluation of D- and L-sugar-containing mono- and bidesmosidic ursane-type saponins. Bioorganic and Medicinal Chemistry, 106
5. Moawad, F., Ruel, Y., Rezaei, N., Alsarraf, J., Pichette, A., Legault, J., Pouliot, R., Brambilla, D. (2024) Microneedles with implantable tip-accumulated therapeutics for the long-term management of psoriasis. Small, 20(51):2405927
6. Benomari, F.Z., Sarazin, M., Chaib, D., Pichette, A., Boumghar, H., Boumghar, Y., Djabou, N. (2023) Chemical Variability and Chemotype Concept of Essential Oils from Algerian Wild Plants. Molecules, 28(11)
7. Gormand, P., Pichette, A., Legault, J., Alsarraf, J. (2023) Synthesis and Cytotoxicity of Monomethylated Betulinic Acid 3-O-α-l-Rhamnopyranosides. ACS Omega, 8(39):36118 – 36125
8. Petitpoisson, L., Pichette, A., Alsarraf, J. (2022) Towards better syntheses of partially methylated carbohydrates? Organic Chemistry Frontiers, 9(19):5414-5425
9. Moshiashvili, G., Pichette, A., Legault, J., Mshvildadze, V. (2022) Chemical Composition and Cytotoxic Activity of Daphne glomerate and D. pontica. Chemistry of Natural Compounds, 58(2):329-331
10. Mejri, H., Ouerghemi, I., Aidi Wannes, W., Haddada, F., Tlili, N., Hammami, M., Dussault, C., Girad-La Lancette, K., Pichette, A., Legault, J. et al. (2022) Phytochemical analysis, antioxidant, anticancer and anti-inflammatory activities of Lycium europaeum fruits. International Journal of Environmental Health Research
11. St-Gelais, A., Maldonado, E., Saavedra, G., Siles-Alvarado, S., Alsarraf, J., Collin, G., Pichette, A. (2021) Essential oils from bolivia. Xv. herzogole, an original monoterpene benzodioxole from an essential oil from pentacalia herzogii (cabrera) cuatrec. Molecules, 26(19)
12. St-Gelais, A., Alsarraf, J., Legault, J., Plourde, J., Pichette, A. (2021) Effect of the Chromone Core Substitution of Dirchromone on the Resultant Biological Activities. Journal of Natural Products, 84(11):2786-2794
13. Nadaraia, N., Kakhabrishvili, M., Barbakadze, N., Mshvildadze, V., Mulkidzhanyan, K., Pichette, A. (2021) Synthesis and Cytotoxic Activity of 5α-Pregnanolone Hydrazones. Chemistry of Natural Compounds, 57(2):395-397
14. Moshiashvili, G., Mchedlidze, K., Aneli, J., Pichette, A., Mshvildadze, V. (2021) Coumarins from Daphne axilliflora (keissl.) pobed. and the anatomical characteristics of its leaves and stems. Georgian medical news (312):145-149
15. Merad, N., Andreu, V., Chaib, S., Augusto, R., Duval, D., Bertrand, C., Boumghar, Y., Pichette, A., Djabou, N. (2021) Essential oils from two apiaceae species as potential agents in organic crops protection. Antibiotics, 10(6)
16. Lion, Q., Pichette, A., Mihoub, M., Mshvildadze, V., Legault, J. (2021) Phenolic extract from aralia nudicaulis L. rhizomes inhibits cellular oxidative stresses. Molecules, 26(15)
17. Lavoie, S., Pierra, J., Legault, J., Raminoson, D., Lion, Q., Mshvildadze, V., Pichette, A. (2021) Isolation and characterization of triterpenoid saponins from leaves of Aralia nudicaulis L. Phytochemistry Letters, 43:184-189
18. Kavtaradze, N., Alaniya, M., Pichette, A., Mshvildadze, V. (2021) Apigenin Glycosides from Astragalus galegiformis. Chemistry of Natural Compounds, 57(1):156-157
19. Grenier, A., Legault, J., Pichette, A., Jean, L., Belanger, A., Pouliot, R. (2021) Antioxidant, anti-inflammatory, and anti-aging potential of a kalmia angustifolia extract and identification of some major compounds. Antioxidants, 10(9)
20. Cote, H., Pichette, A., St-Gelais, A., Legault, J. (2021) The biological activity of monarda Didyma l. Essential oil and its effect as a diet supplement in mice and broiler chicken. Molecules, 26(11)
21. Ardaillou, A., Alsarraf, J., Legault, J., Simard, F., Pichette, A. (2021) Hemisynthesis and biological evaluation of cinnamylated, benzylated, and prenylated dihydrochalcones from a common bio-sourced precursor. Antibiotics, 10(6)
22. Alsarraf, J., Petitpoisson, L., Pichette, A. (2021) Catalytic Site-Selective Carbamoylation of Pyranosides. Organic Letters, 23(15):6052-6056
23. Deslauriers, A., Garcia, L., Charrier, G., Butto, V., Pichette, A., Paré, M. (2021) Cold acclimation and deacclimation in wild blueberry: Direct and indirect influence of environmental factors and non-structural carbohydrates. Agricultural and Forest Meteorology, 301-302
24. St-Gelais, A., Alsarraf, J., Legault, J., Mihoub, M., Pichette, A. (2020) On the role of the vinylsulfoxide side chain of dirchromone towards its bioactivities. Organic and Biomolecular Chemistry, 18(47):9700-9705
25. Nadaraia, N., Barbakadze, N., Mshvildadze, V., Sylla, B., Legault, J., Pichette, A. (2020) Synthesis and Cytotoxicity of Epiandrosterone Hydrazones. Chemistry of Natural Compounds, 56(2):274-277
26. Mercier, S., Lorenzo, R., Pichette, A., Cote, H., Legault, J., St-Gelais, A. (2020) Pili Tree (Canarium ovatum) Resin's Antibacterial Essential Oil and Hydrosol as Rich Sources of (S)-Phellandrenes Derivatives. Chemistry & Biodiversity, 17(12)
27. Boucher, M.-A., Cote, H., Pichette, A., Ripoll, L., Legault, J. (2020) Chemical composition and antibacterial activity of Tussilago farfara (L.) essential oil from Quebec, Canada. Natural Product Research, 34(4):545-548
28. Belanger, A., Grenier, A., Simard, F., Gendreau, I., Pichette, A., Legault, J., Pouliot, R. (2020) Dihydrochalcone derivatives from populus balsamifera l. Buds for the treatment of psoriasis. International Journal of Molecular Sciences, 21(1)
29. Alsarraf, J., Gormand, P., Legault, J., Mihoub, M., Pichette, A. (2020) Synthesis of a first-generation L-rhamnose dendron. Tetrahedron Letters, 61(14)
30. Sylla, B., Lavoie, S., Legault, J., Gauthier, C., Pichette, A. (2019) Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins. RSC Advances, 9(68):39743-39757
31. Cote, H., Pichette, A., Simard, F., Ouellette, M.-E., Ripoll, L., Mihoub, M., Grimard, D., Legault, J. (2019) Balsacone c, a new antibiotic targeting bacterial cell membranes, inhibits clinical isolates of methicillin-resistant staphylococcus aureus (Mrsa) without inducing resistance. Frontiers in Microbiology, 10(OCT)
32. St-Gelais, A., Roger, B., Alsarraf, J., Legault, J., Masse, D., Pichette, A. (2018) Aromas from quebec. VI. Morella pensylvanica from the magdalen islands: A (-)-α-bisabolol-rich oil featuring a new bisabolane ether. Journal of Essential Oil Research, 30(5):319-329
33. St-Gelais, A., Alsarraf, J., Legault, J., Gauthier, C., Pichette, A. (2018) Soft-enolization Baker-Venkataraman Rearrangement Enabled Total Synthesis of Dirchromones and Related 2-Substituted Chromones. Organic Letters, 20(23):7424-7428
34. Pare, M., Legault, J., Pichette, A., Tremblay, C., Aubut, M.-F. (2018) Canadian goldenrod residues and extracts inhibit the growth of Streptomyces scabiei, the causal agent of potato common scab. Canadian Journal of Plant Pathology, 40(1):70-75
35. Nadaraia, N., Kakhabrishvili, M., Barbakadze, N., Mshvildadze, V., Sylla, B., Pichette, A. (2018) Synthesis of some 5α-androstano[17,16-d]pyrazoles from tigogenin. Bulletin of the Georgian National Academy of Sciences, 12(3):110-116
36. Nadaraia, N., Kakhabrishvili, M., Barbakadze, N., Mshvildadze, V., Sylla, B., Legault, J., Pichette, A. (2018) Synthesis and Biological Activity of Steroidal Tigogenin Hydrazones and Pyrazolines. Chemistry of Natural Compounds, 54(5):926-929
37. Nadaraia, N., Barbakadze, N., Kakhabrishvili, M., Sylla, B., Pichette, A., Makhmudov, U. (2018) Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives. Chemistry of Natural Compounds, 54(2):310-314
38. Mihoub, M., Pichette, A., Sylla, B., Gauthier, C., Legault, J. (2018) Bidesmosidic betulin saponin bearing L-rhamnopyranoside moieties induces apoptosis and inhibition of lung cancer cells growth in vitro and in vivo. PLOS ONE, 13(3)
39. Huang, X., Kocaefe, D., Kocaefe, Y., Pichette, A. (2018) Combined effect of acetylation and heat treatment on the physical, mechanical and biological behavior of jack pine (Pinus banksiana) wood. European Journal of Wood and Wood Products, 76(2):525-540
40. St-Gelais, A., Collin, G., Pichette, A. (2017) Aromas from Quebec. V. Essential oils from the fruits and stems of Heracleum maximum Bartram and their unsaturated aliphaticacetates. Journal of Essential Oil Research, 29(2):126-136
41. Lavoie, S., Cote, I., Pichette, A., Gauthier, C., Ouellet, M., Nagau-Lavoie, F., Mshvildadze, V., Legault, J. (2017) Chemical composition and anti-herpes simplex virus type 1 (HSV-1) activity of extracts from Cornus canadensis. BMC Complementary and Alternative Medicine, 17(1)
42. Karakas, F., Turker, A., Karakas, A., Mshvildadze, V., Pichette, A., Legault, J. (2017) In vitro cytotoxic, antibacterial, anti-inflammatory and antioxidant activities and phenolic content in wild-grown flowers of common daisy—A medicinal plant. Journal of Herbal Medicine, 8:31-39
43. Simard, F., Gauthier, C., Legault, J., Lavoie, S., Mshvildadze, V., Pichette, A. (2016) Structure elucidation of anti-methicillin resistant Staphylococcus aureus (MRSA) flavonoids from balsam poplar buds. Bioorganic and Medicinal Chemistry, 24(18):4188-4198
44. Nadaraia, N., Onashvili, E., Kakhabrishvili, M., Barbakadze, N., Sylla, B., Pichette, A. (2016) Synthesis and Antiviral Activity of Several N-Containing 5α-STEROIDS. Chemistry of Natural Compounds, 52(5):853-855
45. Medini, F., Megdiche, W., Mshvildadze, V., Pichette, A., Legault, J., St-Gelais, A., Ksouri, R. (2016) Antiviral-guided fractionation and isolation of phenolic compounds from Limonium densiflorum hydroalcoholic extract. Comptes Rendus Chimie, 19(6):726-732
46. Lavoie, S., Ouellet, M., Fleury, P.-Y., Gauthier, C., Legault, J., Pichette, A. (2016) Complete 1H and 13C NMR assignments of a series of pergalloylated tannins. Magnetic Resonance in Chemistry, 54(2):168-174
47. Cote, H., Boucher, M.-A., Pichette, A., Roger, B., Legault, J. (2016) New antibacterial hydrophobic assay reveals Abies balsamea oleoresin activity against Staphylococcus aureus and MRSA. Journal of Ethnopharmacology, 194:684-689
48. St-Gelais, A., Legault, J., Mshvildadze, V., Pichette, A. (2015) Dirchromones: Cytotoxic Organic Sulfur Compounds Isolated from Dirca palustris. Journal of Natural Products, 78(8):1904-1909
49. St-Gelais, A., Caron, L., Collin, G., Marceau, H., Pichette, A. (2015) Aromas from Quebec. III. Composition of the essential oil and hydrolate of the roots of Anthriscus sylvestris (L.) Hoffm. from Saguenay. Journal of Essential Oil Research, 27(5):373-379
50. Simard, F., Gauthier, C., Chiasson, E., Lavoie, S., Mshvildadze, V., Legault, J., Pichette, A. (2015) Antibacterial Balsacones J-M, Hydroxycinnamoylated Dihydrochalcones from Populus balsamifera Buds. Journal of Natural Products, 78(5):1147-1153
51. Oueslati, S., Ellili, A., Legault, J., Pichette, A., Ksouri, R., Lachaal, M., Karray-Bouraoui, N. (2015) Phenolic content, antioxidant and anti-inflammatory activities of Tunisian Diplotaxis simplex (Brassicaceae). Natural Product Research, 29(12):1189-1191
52. Mskhiladze, L., Chincharadze, D., Mshvildadze, V., Pichette, A., Frederich, M., Ollivier, E., Elias, R. (2015) Steroidal Glycosides from the Flowers of Allium leucanthum. Chemistry of Natural Compounds, 51(5):900-904
53. Lavoie, S., Gauthier, C., Mshvildadze, V., Legault, J., Roger, B., Pichette, A. (2015) DFT Calculations and ROESY NMR Data for the Diastereochemical Characterization of Cytotoxic Tetraterpenoids from the Oleoresin of Abies balsamea. Journal of Natural Products, 78(12):2896-2907
54. Hock, V., Chouinard, G., Lucas, E., Cormier, D., Leskey, T., Wright, S., Zhang, A., Pichette, A. (2015) Behavioral responses of plum curculio (Coleoptera: Curculionidae) to different enantiomer concentrations and blends of the synthetic aggregation pheromone grandisoic acid. Journal of Economic Entomology, 108(2):549-558
55. Getia, M., Dekanosidze, G., Mshvildadze, V., Pichette, A. (2015) Development of analytical procedure for the quantitative validation of bronchospasmolitic thick extract from caucasian ivy. Acta Horticulturae, 1098:111-116
56. Sylla, B., Gauthier, C., Legault, J., Fleury, P.-Y., Lavoie, S., Mshvildadze, V., Muzashvili, T., Kemertelidze, E., Pichette, A. (2014) Isolation of a new disaccharide nucleoside from Helleborus caucasicus: Structure elucidation and total synthesis of hellecaucaside A and its β-anomer. Carbohydrate Research, 398:80-89
57. Simard, F., Legault, J., Lavoie, S., Pichette, A. (2014) Balsacones D-I, dihydrocinnamoyl flavans from Populus balsamifera buds. Phytochemistry, 100:141-149
58. Piochon-Gauthier, M., Legault, J., Sylvestre, M., Pichette, A. (2014) The essential oil of Populus balsamifera buds: Its chemical composition and cytotoxic activity. Natural Product Communications, 9(2):257-260
59. Oueslati, S., Ksouri, R., Pichette, A., Lavoie, S., Girard-Lalancette, K., Mshvildadze, V., Abdelly, C., Legault, J. (2014) A new flavonol glycoside from the medicinal halophyte Suaeda fruticosa. Natural Product Research, 28(13):960-966
60. Nadaraia, N., Kakhabrishvili, M., Onashvili, E., Barbakadze, N., Getia, M., Pichette, A., Sikharulidze, M., Makhmudov, U. (2014) Synthesis of several 5α-androstano[17,16-d]pyrazolines from tigogenin. Chemistry of Natural Compounds, 50(6):1024-1028
61. Medini, F., Legault, J., Pichette, A., Abdelly, C., Ksouri, R. (2014) Antiviral efficacy of Limonium densiflorum against HSV-1 and influenza viruses. South African Journal of Botany, 92:65-72
62. Hock, V., Chouinard, G., Lucas, E., Cormier, D., Leskey, T., Wright, S., Zhang, A., Pichette, A. (2014) Establishing abiotic and biotic factors necessary for reliable male pheromone production and attraction to pheromones by female plum curculios Conotrachelus nenuphar (Coleoptera: Curculionidae). Canadian Entomologist, 146(5):528-547
63. Alaniya, M., Sutiashvili, M., Shalashvili, K., Skhirtladze, A., Mshvildadze, V., Pichette, A. (2014) Iridoid glycosides from roots of Verbascum laxum. Chemistry of Natural Compounds, 50(5):842-845
64. Sutiashvili, M., Alaniya, M., Mshvildadze, V., Skhirtladze, A., Pichette, A., Lavoie, S. (2013) Flavonoid and cycloartane glycosides from seeds of Koelreuteria paniculata. Chemistry of Natural Compounds, 49(2):395-397
65. Saha, S., Kocaefe, D., Krause, C., Boluk, Y., Pichette, A. (2013) Enhancing exterior durability of heat-treated jack pine by photo-stabilization by acrylic polyurethane coating using bark extract. Part 2: Wetting characteristics and fluorescence microscopy analysis. Progress in Organic Coatings, 76(2-3):504-512
66. Saha, S., Kocaefe, D., Boluk, Y., Mshvildadze, V., Legault, J., Pichette, A. (2013) Boreal forest conifer extracts: Potential natural additives for acrylic polyurethane coatings for the protection of heat-treated jack pine. Journal of Coatings Technology and Research, 10(1):109-122
67. Saha, S., Kocaefe, D., Boluk, Y., Pichette, A. (2013) Surface degradation of CeO 2 stabilized acrylic polyurethane coated thermally treated jack pine during accelerated weathering. Applied Surface Science, 276:86-94
68. Legault, J., Girard-Lalancette, K., Dufour, D., Pichette, A. (2013) Antioxidant potential of bark extracts from boreal forest conifers. Antioxidants, 2(3):77-89
69. Legault, J., Cote, P.-A., Ouellet, S., Simard, S., Pichette, A. (2013) Iso-caryophyllene cytotoxicity induced by lipid peroxidation and membrane permeabilization in L-929 cells. Journal of Applied Pharmaceutical Science, 3(8):25-31
70. Lavoie, S., Legault, J., Simard, F., Chiasson, E., Pichette, A. (2013) New antibacterial dihydrochalcone derivatives from buds of Populus balsamifera. Tetrahedron Letters, 54(13):1631-1633
71. Lavoie, S., Gauthier, C., Legault, J., Mercier, S., Mshvildadze, V., Pichette, A. (2013) Lanostane- and cycloartane-type triterpenoids from abies balsamea oleoresin. Beilstein Journal of Organic Chemistry, 9:1333-1339
72. Caron, L., Deslauriers, A., Mshvildadze, V., Pichette, A. (2013) Volatile compounds in the foliage of balsam fir analyzed by static headspace gas chromatography (HS-GC): An example of the spruce budworm defoliation effect in the boreal forest of Quebec, Canada. Microchemical Journal, 110:587-590
73. Thibeault, D., Gauthier, C., Legault, J., Bouchard, J., Gagne, L., Pichette, A. (2012) Synthesis and cytotoxicity of lupane-type triterpenoid glyceryl esters. Bioorganic & Medicinal Chemistry Letters, 22(14):4735-4739
74. Oueslati, S., Ksouri, R., Falleh, H., Pichette, A., Abdelly, C., Legault, J. (2012) Phenolic content, antioxidant, anti-inflammatory and anticancer activities of the edible halophyte Suaeda fruticosa Forssk. Food Chemistry, 132(2):943-947
75. Lavoie, S., Legault, J., Gauthier, C., Mshvildadze, V., Mercier, S., Pichette, A. (2012) Abibalsamins A and B, two new tetraterpenoids from Abies balsamea oleoresin. Organic Letters, 14(6):1504-1507
76. Huang, X., Kocaefe, D., Kocaefe, Y., Boluk, Y., Pichette, A. (2012) A spectrocolorimetric and chemical study on color modification of heat-treated wood during artificial weathering. Applied Surface Science, 258(14):5360-5369
77. Huang, X., Kocaefe, D., Kocaefe, Y., Boluk, Y., Pichette, A. (2012) Study of the degradation behavior of heat-treated jack pine (Pinus banksiana) under artificial sunlight irradiation. Polymer Degradation and Stability, 97(7):1197-1214
78. Huang, X., Kocaefe, D., Kocaefe, Y., Boluk, Y., Pichette, A. (2012) Changes in wettability of heat-treated wood due to artificial weathering. Wood Science and Technology, 46(6):1215-1237
79. Huang, X., Kocaefe, D., Boluk, Y., Kocaefe, Y., Pichette, A. (2012) Effect of surface preparation on the wettability of heat-treated jack pine wood surface by different liquids. European Journal of Wood and Wood Products, 70(5):711-717
80. Georges, P., Legault, J., Lavoie, S., Grenon, C., Pichette, A. (2012) Diterpenoids from the buds of Pinus banksiana lamb. Molecules, 17(8):9716-9727
81. Garneau, F.-X., Collin, G., Gagnon, H., Pichette, A. (2012) Chemical composition of the hydrosol and the essential oil of three different species of the pinaceae family : Picea glauca (moench) voss., picea mariana (mill.) b.s.p., and abies balsamea (l.) mill. Journal of Essential Oil Bearing Plants, 15(2):227-236
82. Bourgou, S., Pichette, A., Marzouk, B., Legault, J. (2012) Antioxidant, anti-inflammatory, anticancer and antibacterial activities of extracts from nigella sativa (black cumin) plant parts. Journal of Food Biochemistry, 36(5):539-546
83. Bourgou, S., Pichette, A., Lavoie, S., Marzouk, B., Legault, J. (2012) Terpenoids isolated from Tunisian Nigella sativa L. essential oil with antioxidant activity and the ability to inhibit nitric oxide production. Flavour and Fragrance Journal, 27(1):69-74
84. Saha, S., Kocaefe, D., Sarkar, D., Boluk, Y., Pichette, A. (2011) Effect of TiO2-containing nano-coatings on the color protection of heat-treated jack pine. Journal of Coatings Technology and Research, 8(2):183-190
85. Saha, S., Kocaefe, D., Boluk, Y., Pichette, A. (2011) Enhancing exterior durability of jack pine by photo-stabilization of acrylic polyurethane coating using bark extract. Part 1: Effect of UV on color change and ATR-FT-IR analysis. Progress in Organic Coatings, 70(4):376-382
86. Legault, J., Perron, T., Mshvildadze, V., Girard-Lalancette, K., Perron, S., Laprise, C., Sirois, P., Pichette, A. (2011) Antioxidant and anti-inflammatory activities of quercetin 7-O-β-D-glucopyranoside from the leaves of brasenia schreber. Journal of Medicinal Food, 14(10):1127-1134
87. Legault, J., Larouche, P.-L., Cote, I., Bouchard, L., Pichette, A., Robinson, B., Morin, C. (2011) Low-concentration methylene blue maintains energy production and strongly improves survival of Leigh syndrome French Canadian skin fibroblasts. Journal of Pharmacy and Pharmaceutical Sciences, 14(3):438-449
88. Kavtaradze, N., Alaniya, M., Mshvildadze, V., Skhirtladze, A., Lavoie, S., Pichette, A. (2011) Flavonoids from Astragalus microcephalus. Chemistry of Natural Compounds, 46(6):971-973
89. Jonville, M., Kodja, H., Strasberg, D., Pichette, A., Ollivier, E., Frederich, M., Angenot, L., Legault, J. (2011) Antiplasmodial, anti-inflammatory and cytotoxic activities of various plant extracts from the Mascarene Archipelago. Journal of Ethnopharmacology, 136(3):525-531
90. Getiya, M., Gabelaya, M., Mshvildadze, V., Pichette, A., Lavoie, S., Dekanosidze, G. (2011) A new triterpene glycoside from fruit of Phytolacca americana. Chemistry of Natural Compounds, 47(5):764-766
91. Gauthier, C., Legault, J., Piochon-Gauthier, M., Pichette, A. (2011) Advances in the synthesis and pharmacological activity of lupane-type triterpenoid saponins. Phytochemistry Reviews, 10(4):521-544
92. Bellila, A., Tremblay, C., Pichette, A., Marzouk, B., Mshvildadze, V., Lavoie, S., Legault, J. (2011) Cytotoxic activity of withanolides isolated from Tunisian Datura metel L. Phytochemistry, 72(16):2031-2036
93. Alaniya, M., Kavtaradze, N., Lavoie, S., Pichette, A., Mshvildadze, V., Apakidze, Z. (2011) Chemical constituents of the aerial part of Astragalus bungeanus. Chemistry of Natural Compounds, 46(6):1001-1003
94. Thibeault, D., Legault, J., Gauthier, C., Lavoie, S., Bouchard, J., Pichette, A. (2010) Acid-catalyzed E-ring expansion and isomerization of 3-acetylbetulin: Synthesis of cytotoxic anhydrobetulin saponins. Synthetic Communications, 40(2):213-221
95. Piochon, M., Legault, J., Pichette, A. (2010) Chemical composition of the essential oil from solidago puberula nutt. Growing wild in the north of Quebec. Journal of Essential Oil Research, 22(3):228-229
96. Pichette, A., Eftekhari, A., Georges, P., Lavoie, S., Mshvildadze, V., Legault, J. (2010) Cytotoxic phenolic compounds in leaf buds of Populus tremuloides. Canadian Journal of Chemistry, 88(2):104-110
97. Ngoumfo, R., Jouda, J.-B., Mouafo, F., Komguem, J., Mbazoa, C., Shiao, T., Choudhary, M., Laatsch, H., Legault, J., Pichette, A. et al. (2010) In vitro cytotoxic activity of isolated acridones alkaloids from Zanthoxylum leprieurii Guill. et Perr. Bioorganic and Medicinal Chemistry, 18(10):3601-3605
98. Legault, J., Girard-Lalancette, K., Grenon, C., Dussault, C., Pichette, A. (2010) Antioxidant activity, inhibition of nitric oxide overproduction, and in vitro antiproliferative effect of maple sap and syrup from Acer saccharum. Journal of Medicinal Food, 13(2):460-468
99. Collin, G., Garneau, F.-X., Gagnon, H., Pichette, A., Lavoie, S. (2010) Analysis of cymenes in essential oils: The case of lepechinia meyeni (walp.) epling. Journal of Essential Oil Research, 22(4):310-313
100. Bourgou, S., Pichette, A., Marzouk, B., Legault, J. (2010) Bioactivities of black cumin essential oil and its main terpenes from Tunisia. South African Journal of Botany, 76(2):210-216
101. Belanger, A., Collin, G., Garneau, F., Gagnon, H., Pichette, A. (2010) Aromas From Quebec. II. Composition of the essential oil of the rhizomes and roots of asarum canadense L. Journal of Essential Oil Research, 22(2):164-169
102. Poncsak, S., Kocaefe, D., Simard, F., Pichette, A. (2009) Evolution of extractive composition during thermal treatment of Jack pine. Journal of Wood Chemistry and Technology, 29(3):251-264
103. Piochon, M., Legault, J., Gauthier, C., Pichette, A. (2009) Synthesis and cytotoxicity evaluation of natural α-bisabolol β-d-fucopyranoside and analogues. Phytochemistry, 70(2):228-236
104. Pedieu, R., Ried, B., Pichette, A. (2009) Properties of birch outer bark panels reinforced with wood strands in the surface layers. BioResources, 4(2):771-788
105. Pedieu, R., Riedl, B., Pichette, A. (2009) Properties of mixed particleboards based on white birch (Betula papyrifera) inner bark particles and reinforced with wood fibres [Eigenschaften dreischichtiger spanplatten aus bastpartikeln der papierbirke (Betula papyrifera) verstärkt mit holzfasern]. European Journal of Wood and Wood Products, 67(1):95-101
106. Naasz, R., Caron, J., Legault, J., Pichette, A. (2009) Efficiency Factors for Bark Substrates: Biostability, Aeration, or Phytotoxicity. Soil Science Society of America Journal, 73(3):780-791
107. Leskey, T., Wright, S., Anger, W., Chouinard, G., Cormier, D., Pichette, A., Zhang, A. (2009) Electroantennogram technique for conotrachelus nenuphar (Coleoptera: Curculionidae). Environmental Entomology, 38(3):870-878
108. Girard-Lalancette, K., Pichette, A., Legault, J. (2009) Sensitive cell-based assay using DCFH oxidation for the determination of pro- and antioxidant properties of compounds and mixtures: Analysis of fruit and vegetable juices. Food Chemistry, 115(2):720-726
109. Gauthier, C., Legault, J., Rondeau, S., Pichette, A. (2009) Synthesis of betulinic acid acyl glucuronide for application in anticancer prodrug monotherapy. Tetrahedron Letters, 50(9):988-991
110. Gauthier, C., Legault, J., Piochon, M., Lavoie, S., Tremblay, S., Pichette, A. (2009) Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products. Bioorganic & Medicinal Chemistry Letters, 19(8):2310-2314
111. Gauthier, C., Legault, J., Pichette, A. (2009) Recent progress in the synthesis of naturally occurring triterpenoid saponins. Mini-Reviews in Organic Chemistry, 6(4):321-344
112. Gauthier, C., Legault, J., Lavoie, S., Rondeau, S., Tremblay, S., Pichette, A. (2009) Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins. Journal of Natural Products, 72(1):72-81
113. Gauthier, C., Legault, J., Girard-Lalancette, K., Mshvildadze, V., Pichette, A. (2009) Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins. Bioorganic and Medicinal Chemistry, 17(5):2002-2008
114. Alaniya, M., Kavtaradze, N., Lavoi, S., Pichette, A., Mshvildadze, V. (2009) Aurone from Astragalus microcephalus stems. Chemistry of Natural Compounds, 45(3):455-456
115. Simard, F., Legault, J., Lavoie, S., Mshvildadze, V., Pichette, A. (2008) Isolation and identification of cytotoxic compounds from the wood of Pinus resinosa. Phytotherapy Research, 22(7):919-922
116. Pedieu, R., Ried, B., Pichette, A. (2008) Physical and mechanical properties of panel based on outer bark particles of white birch: Mixed panels with wood particles versus wood fibres. Maderas: Ciencia y Tecnologia, 10(3):195-206
117. Pedieu, R., Riedl, B., Pichette, A. (2008) Measurement of wood and bark particles acidity and their impact on the curing of urea formaldehyde resin during the hot pressing of mixed panels [Messung der Acidität von Holzspänen und Rindenpartikeln Sowie Deren Einfluss auf die Aushärtung von Harnstoffformaldehydharz Beim Heißpressen von Spanplatten]. Holz als Roh - und Werkstoff, 66(2):113-117
118. Pedieu, R., Riedl, B., Pichette, A. (2008) Properties of white birch (Betula papyrifera) outer bark particleboards with reinforcement of coarse wood particles in the core layer. Annals of Forest Science, 65(7)
119. Mskhiladze, L., Legault, J., Lavoie, S., Mshvildadze, V., Kuchukhidze, J., Elias, R., Pichette, A. (2008) Cytotoxic steroidal saponins from the flowers of Allium leucanthum. Molecules, 13(12):2925-2934
120. Gauthier, C., Legault, J., Lavoie, S., Rondeau, S., Tremblay, S., Pichette, A. (2008) Synthesis of two natural betulinic acid saponins containing α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranose and their analogues. Tetrahedron, 64(30-31):7386-7399
121. Garneau, F.-X., Collin, G., Gagnon, H., Belanger, A., Lavoie, S., Savard, N., Pichette, A. (2008) Aromas from Quebec. I. Composition of the essential oil of the rhizomes of acorus calamus L. Journal of Essential Oil Research, 20(3):250-254
122. Bradette-Hebert, M.-E., Legault, J., Lavoie, S., Pichette, A. (2008) A new labdane diterpene from the flowers of Solidago canadensis. Chemical and Pharmaceutical Bulletin, 56(1):82-84
123. Thibeault, D., Legault, J., Bouchard, J., Pichette, A. (2007) Useful approach to access germanicanes from betulin. Tetrahedron Letters, 48(48):8416-8419
124. Thibeault, D., Gauthier, C., Legault, J., Bouchard, J., Dufour, P., Pichette, A. (2007) Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulin. Bioorganic and Medicinal Chemistry, 15(18):6144-6157
125. Sylvestre, M., Pichette, A., Longtin, A., De Ker Martin, M.-A., Bercion, S., Legault, J. (2007) Chemical composition of leaf essential oil of hedyosmum arborescens and evaluation of its anticancer activity. Natural Product Communications, 2(12):1269-1272
126. Sylvestre, M., Pichette, A., Lavoie, S., Longtin, A., Legault, J. (2007) Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter. Phytotherapy Research, 21(6):536-540
127. Mshvildadze, V., Legault, J., Lavoie, S., Gauthier, C., Pichette, A. (2007) Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera. Phytochemistry, 68(20):2531-2536
128. Legault, J., Pichette, A. (2007) Potentiating effect of β-caryophyllene on anticancer activity of α-humulene, isocaryophyllene and paclitaxel. Journal of Pharmacy and Pharmacology, 59(12):1643-1647
129. Kocaefe, D., Chaudhry, B., Poncsak, S., Bouazara, M., Pichette, A. (2007) Thermogravimetric study of high temperature treatment of aspen: Effect of treatment parameters on weight loss and mechanical properties. Journal of Materials Science, 42(3):854-866
130. Dufour, D., Pichette, A., Mshvildadze, V., Bradette-Hebert, M.-E., Lavoie, S., Longtin, A., Laprise, C., Legault, J. (2007) Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius. Journal of Ethnopharmacology, 111(1):22-28
131. Alaniya, M., Kavtaradze, N., Mshvildadze, V., Lavoi, S., Pichette, A. (2007) Coniferyl alcohol glucoside from Astragalus bungeanus. Chemistry of Natural Compounds, 43(6):706-707
132. Alaniya, M., Kavtaradze, N., Gigoshvili, T., Lavoi, S., Pichette, A., Mshvildadze, V. (2007) Cyclocanthoside e from Astragalus caucasicus. Chemistry of Natural Compounds, 43(6):758-759
133. Alaniya, M., Gigoshvili, T., Kavtaradze, N., Lavoi, S., Pichette, A., Mshvildadze, V. (2007) Cyclocephalogenin and cyclogalegigenin from Astragalus caucasicus. Chemistry of Natural Compounds, 43(3):361-362
134. Sylvestre, M., Pichette, A., Longtin, A., Nagau, F., Legault, J. (2006) Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe. Journal of Ethnopharmacology, 103(1):99-102
135. Sylvestre, M., Legault, J., Lavoie, S., Pichette, A. (2006) Investigation of leaf essential oil of myrica gale L. From Quebec: Purification and analysis of oxygenated fractions. Journal of Essential Oil Research, 18(1):38-41
136. Poncsak, S., Kocaefe, D., Bouazara, M., Pichette, A. (2006) Effect of high temperature treatment on the mechanical properties of birch (Betula papyrifera). Wood Science and Technology, 40(8):647-663
137. Pichette, A., Lavoie, S., Morin, P., Mshvildadze, V., Lebrun, M., Legault, J. (2006) New labdane diterpenes from the stem bark of Larix laricina. Chemical and Pharmaceutical Bulletin, 54(10):1429-1432
138. Pichette, A., Larouche, P.-L., Lebrun, M., Legault, J. (2006) Composition and antibacterial activity of Abies balsamea essential oil. Phytotherapy Research, 20(5):371-373
139. Gauthier, C., Legault, J., Lebrun, M., Dufour, P., Pichette, A. (2006) Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents. Bioorganic and Medicinal Chemistry, 14(19):6713-6725
140. Garneau, F.-X., Collin, G., Gagnon, H., Jean, F.-I., Strobl, H., Pichette, A. (2006) The essential oil composition of devil's club, Oplopanax horridus J. E. Smith Miq. Flavour and Fragrance Journal, 21(5):792-794
141. Sylvestre, M., Legault, J., Dufour, D., Pichette, A. (2005) Chemical composition and anticancer activity of leaf essential oil of Myrica gale L. Phytomedicine, 12(4):299-304
142. Stevanovic, T., Garneau, F.-X., Jean, F.-I., Gagnon, H., Vilotic, D., Petrovic, S., Ruzic, N., Pichette, A. (2005) The essential oil composition of Pinus mugo Turra from Serbia. Flavour and Fragrance Journal, 20(1):96-97
143. Pichette, A., Garneau, F.-X., Collin, G., Jean, F.-I., Gagno, H., Arze, J. (2005) Essential Oils from Bolivia. IV. Compositae: Tagetes aff. maxima Kuntze and Tagetes multiflora H.B.K. Journal of Essential Oil Research, 17(1):27-28
144. Arze, J., Jean, F., Gagnon, H., Collin, G., Garneau, F., Pichette, A. (2005) Essential oils from bolivia. VII. Myrtaceae: Myrcianthes osteomeloides (Rusby) McVaugh and Myrcianthes pseudomato (Legrand) McVaugh. Journal of Essential Oil Research, 17(1):64-65
145. Pichette, A., Liu, H., Roy, C., Tanguay, S., Simard, F., Lavoie, S. (2004) Selective oxidation of betulin for the preparation of betulinic acid, an antitumoral compound. Synthetic Communications, 34(21):3925-3937
146. Garneau, F.-X., Riedl, B., Hobbs, S., Pichette, A., Gagnon, H. (2004) The use of sensor array technology for rapid differentiation of the sapwood and heartwood of Eastern Canadian spruce, fir and pine. Holz als Roh - und Werkstoff, 62(6):470-473
147. Pichette, A., Garneau, F.-X., Collin, G., Jean, F.-I., Riedl, B. (2003) Estimation of jack pine, black spruce, and balsam fir proportions in wood chips. Journal of Wood Chemistry and Technology, 23(2):131-140
148. Legault, J., Dahl, W., Debiton, E., Pichette, A., Madelmont, J.-C. (2003) Antitumor activity of balsam fir oil: Production of reactive oxygen species induced by α-humulene as possible mechanism of action. Planta Medica, 69(5):402-407
149. Guidoin, M.-F., Yang, J., Pichette, A., Roy, C. (2003) Betulin isolation from birch bark by vacuum and atmospheric sublimation. A thermogravimetric study. Thermochimica Acta, 398(1-2):153-166
150. Lavoie, S., Pichette, A., Garneau, F.-X., Girard, M., Gaudet, D. (2001) Synthesis of betulin derivatives with solid supported reagents. Synthetic Communications, 31(10):1565-1571
151. Pichette, A., Drouin, N., Girard, M. (2000) Analysis of human parathyroid hormone (1-84) products: Separation of a major impurity in synthetic products by ion-pairing reversed-phase high- performance liquid chromatography. Journal of Chromatography A, 890(1):127-133
152. Garneau, F.-X., Pichette, A., Gagnon, H., Jean, F.-I., Addae-Mensah, I., Osei-Safu, D., Asomaning, W., Oteng-Yeboah, A., Moudachirou, M., Koumaglo, K. (2000) (E)- and (Z)-Foeniculin, Constituents of the Leaf Oil of a New Chemovariety of Clausena anisata. Journal of Essential Oil Research, 12(6):757-762
153. Pichette, A., Garneau, F.-X., Jean, F.-I., Riedl, B., Girard, M. (1998) Chemical differences between the wood extracts of jack pine (Pinus banksiana), black spruce (Picea mariana) and balsam fir (Abies balsamea) from Eastern Canada. Journal of Wood Chemistry and Technology, 18(4):427-438
154. Pichette, A., Voyer, N., Larouche, R., Meillon, J.-C. (1997) A useful method for the preparation of fully protected peptide acids and esters. Tetrahedron Letters, 38(8):1279-1282

Articles publiés dans des actes de colloque (proceedings)

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Rapports scientifiques, manuels et autres

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Thèses, mémoires et essais

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Thèses, mémoires et essais supervisés

1. Girard, L. (2024) Mise au point d’un nouveau test antiviral in vitro contre le coronavirus HCoV-OC43 et évaluation de l’huile essentielle des bourgeons de P. balsamifera. Mémoire de maîtrise, Université du Québec à Chicoutimi
2. Dubreuil, M. (2024) Extraction enzymatique du myrique baumier (Myrica gale L) et évaluation de l’activité biologique des extraits. Mémoire de maîtrise, Université du Québec à Chicoutimi

Articles non révisés par un comité de lecture

1. Piochon, M., Pichette, A., Legault, J., Mshvildadze, V. (2023) Plantes de la forêt boréale : de la médecine traditionnelle autochtone à la médecine moderne. The Conversation
2. Alsarraf, J., Pichette, A., Legault, J. (2023) Vers une valorisation des ressources végétales boréales. The Conversation